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KMID : 0604520070330020069
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Journal of the Society of Cosmetic Scientists of Korea
2007 Volume.33 No. 2 p.69 ~ p.77
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The Study on the Whitening Effects and Antioxidant Activity of Various Citrus Fruits
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Kim Han-Sung
Lee Chan-Woo
Kim Duck-Hee
Kim Gi-Ok
Kim Se-Jae
Chang Ih-Seop
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Abstract
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We examined the depigmentation effect on Korean traditional citrus 17 species. With B16 melanoma cells, we have seen inhibition of the tyrosinase and melanin formation, which eventually were dose dependently decreased by three citrus fruits, immature Citrus unshiu, Citrus hassaku, and Citrus sinensis reticulata as compared with positive control. Also, we examined expression of tyrosinase, DOPAchrome tautomerase (TRP-2), and DHICA oxidase (TRP-1) which affect melanin synthesis. Especially, immature Citrus unshiu decreased the protein levels of tyrosinase and TRP-1. In conclusion, immature Citrus unshue showed the strongest activity in all the experiments mentioned above and we expect that it can be used for preventing UV-induced pigmentation.
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KEYWORD
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malanin, antioxidative, TRP-1, TRP-2, depigment, immature Citrus unshiu, Citro hassaku
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